- EGFR (Epidermal Growth Factor Receptor) Antibody
- MyBioSource.com
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- MBS4380854
- 0.5 mL
- Monoclonal
- Human
- Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide. Contact us if you require this Ab in a different format
- Flow Cytometry (FC/FACS), Immunofluorescence (IF)
- Mouse
- ~170kDa (wild type) and ~145kDa (vIII variant)
- EGFR (Epidermal Growth Factor Receptor)
- Purified Ab conjugated to CF488
- epidermal growth factor receptor
- PIG61, ERBB1, NISBD2, ERBB, HER1, mENA
- Unconjugated
- IgG2a kappa
- GFR450
Specifications/Features
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas